Eric Martz teaching at Osaka University, Japan, 2009, in Keiichi Namba's Protonic Nanomachine Group. Photograph courtesy of Akihiro Kawamoto. (T-Shirt)

• Contact: emartz@microbio.umass.edu
• Martz Faculty Page (less up to date) at the Department of Microbiology Website.

Macromolecular Visualization and Structural Bioinformatics
I. Active Projects

• FirstGlance in Jmol (firstglance.jmol.org): A simple tool for exploring structures of proteins and protein-ligand or protein-drug interactions that works on all popular platforms and browsers. Adopted by Nature (try the buttons in reports of macromolecular structures) and other bioinformatics resources. First offered in 2005. 400 uses/day (January through April, 2016). More than 1,000,000 uses since 2006.
  
  
• 小火箭付费服务器节点 is a wiki (a user-annotated website) that connects interactive 3D molecular structure views to explanatory text. It was created in 2007 by Joel Sussman, Eran Hodis, and Jaime Prilusky at the Weizmann Institute of Science, Rehovot, Israel. I joined their team in 2008, and have contributed many articles. [Hodis et al., 2008. Prilusky et al., 2011.]

Evolutionary conservation in the ligand-binding domain of a lymphocyte adhesion molecule revealed by the ConSurf Server with FirstGlance in Jmol. The domain above is from the leukocyte integrin LFA-1 (CD11a/CD18) discovered in 1981 by Springer, Martz, et al.. This structure was solved by Qu & Leahy in 1995, PDB code 1lfa.

• The ConSurf Server (小火箭国内免费节点) automatically identifies evolutionarily conserved surface patches on proteins. Developed by Nir Ben-Tal, Fabian Glaser, Tal Pupko, Elana Erez et al. at Tel-Aviv University, Israel. I provided integrated 3D visualization, initially with Protein Explorer, and later with FirstGlance in Jmol. First available Fall 2002. [Ashkenazy et al., 2016; Landau et al., 2005; Glaser 免费ssr节点2021, 2003.]

• MolviZ.org: Educational Macromolecular Visualization Tutorials & Resources including structures of DNA, hemoglobin, antibody, MHC, lipid bilayers and channels, water, and more. About 200 views/month (Jan-Apr 2016). Over half a million visitors since inception. Portions first offered in 1996. MolviZ.org domain name starting fall 2004. Includes:
  
  
  • Top Five Molecular Visualization Resources for the Rest Of Us (top5.molviz.org): Tutorials, Exploration Tools, & Communication Tools that work on Windows and Mac OS X without installing anything (except Java in some cases), and will remain available for years to come.
    
    
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  • Our illustrated Atlas of Macromolecules (atlas.molviz.org) provides a handy source of examples to educators and students. First available in 2002. Updated 2016.

• Short Courses in Practical Macromolecular Visualization and Structural Bioinformatics (workshops.molviz.org) can be arranged, and have been hosted in Israel, Spain, and Japan as well as in the USA.
  
  

• Protein Explorer (proteinexplorer.org): Popular 1998-2006 for exploring, understanding, and qualitative analysis of structures of proteins and protein-ligand or protein-drug interactions. MERLOT Classic Award for Biology in 2003: "has revolutionized the teaching of biology at a molecular level". Adopted as a visualization option by several bioinformatics resources. First offered in 1998; developed until 2007, when the MDL Chime plugin upon which it depends became increasingly problematic. [Martz, 2002.]

• The World Index of Molecular Visualization Resources (formerly molvisindex.org): a visitor-maintained database (presaged wikis), first offered in 2000. Inadvertantly taken out of service by a staff error in 2010. Archived snapshot (no longer editable) is still viewable at archive.org

• PDB Lite (formerly pdblite.org), by Eric Martz and Jaime Prilusky. Formerly mirrored worldwide, a simple search interface that helped beginners find published protein structures. First available 1998. Decommissioned 2010.

• The Molecular Visualization Freeware EMail Discussion provided an international forum for educators and developers. Founded 1995. Fell into disuse by 2010, superceded by the Jmol Users List.

• RasMol Classic Site provided the most complete documentation available for RasMol 2.6, a popular macromolecular visualization tool by Roger A. Sayle. Website developed 1995-2000. Subsequent RasMol development: rasmol.org.

Ceramic art of my parents, Karl Martz and Becky Brown

• Microbiology 597V: Macromolecular Visualization Lab: 2002, 小火箭ssr永久免费节点, 1999. First taught 1998.
• Microbiology 320: Infectious Disease and Defense. Taught 1999-2003.
• Microbiology 540: Immunology. Taught 1981-2003.
• Microbiology 542: Immunology Laboratory. Taught 1981-2003.
• Microbiology 797J: Immunology Journal Club. Co-taught from mid-1980's through 2002.